Helen Frankenthaler Foundation

Acetyl Tetrapeptide-22 CAS NO.1295648-76-8

Acetyl Tetrapeptide-3 (acetate)

Acetyl Tetrapeptide-3 (acetate)

A biomimetic peptide

Technical Information

Formal NameN 2-acetyl-L-lysylglycyl-L-histidyl-L-lysinamide, acetate
Molecular FormulaC 22 H 39 N 9 O 5• XC 2 H 4 O 2
Formula Weight509.6
Purity≥95%
FormulationA solid
SolubilityDMF: 14 mg/ml DMSO: 10 mg/ml Ethanol: 10 mg/ml PBS (pH 7.2): 10 mg/ml Water: 10 mg/ml
SMILESO=C(N[C@@H](CC1=CN=CN1)C(N[C@@H](CCCCN)C(N)=O)=O)CNC([C@H](CCCCN)NC(C)=O)=O.OC(C)=O
InChi CodeInChI=1S/C22H39N9O5.C2H4O2/c1-14(32)29-17(7-3-5-9-24)21(35)27-12-19(33)30-18(10-15-11-26-13-28-15)22(36)31-16(20(25)34)6-2-4-8-23;1-2(3)4/h11,13,16-18H,2-10,12,23-24H2,1H3,(H2,25,34)(H,26,28)(H,27,35)(H,29,32)(H,30,33)(H,31,36);1H3,(H,3,4)/t16-,17-,18-;/m0./s1
InChi KeyABOZUSDFQLCWFB-UVJOBNTFSA-N

Shipping & Storage Information

Storage-20°C
ShippingWet ice in continental US; may vary elsewhere

Product Description

Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 μM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin explants.

WARNING This product is not for human or veterinary use.

References & Product Citations

Product Description References

  • Loing, E., Lachance, R., Ollier, V., et al.A new strategy to modulate alopecia using a combination of two specific and unique ingredients. J. Cosmet Sci. 64(1), 45-58 (2013).

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

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