Helen Frankenthaler Foundation

Anti puffiness cosmetic ingredient

Bellahut Pentapeptide-18 Wrinkle Depth Reducer With Pentapeptide-18

Caution

Do not apply undiluted peptides or additives directly onto your skin. This product should be added to a formulation at the recommended usage rate. You can use Bellahut's premium cream or gel as your base for your formulation.

Overview

With the ability to reduce the depth of expression wrinkles up to 24.6% this key ingredient is a must have in any anti-aging cream. Add this to Bellahut's premium cream and combine with any number of our other premium peptides and make an extremely high quality cream that is tailored exactly for your needs.

Pentapeptide-18 reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes. It targets the wrinkle-formation mechanism of expression wrinkles in a new way, offering an alternative to peptides like Acetyl hexapeptide-3.

Pentapeptide-18 is a peptide to reduce expression wrinkles that offers two main advantages:

  • A new and alternative in vitro mechanism to fight expression wrinkles.
  • An additive / synergistic effect to complement the action of Acetyl hexapeptide-3 and other peptides.

Mechanism of Action

Pentapeptide-18's mechanism mimics in vitro the natural mechanism of enkephalins: it couples to the enkephalin receptor, on the outside of the nerve cells. When Pentapeptide-18 couples to the receptor, a conformational change initiates a cascade inside the neuron that results in a decrease of its excitability: the nerve cell’s activity is “turned down” and the release of acetylcholine is modulated. Muscle contraction will be relaxed and therefore, expression wrinkles can be diminished.

Product Details

Incorporation

Pentapeptide-18 Peptide Solution should be incorporated at the end of the emulsion, at cool down, below 40C (104F).

Suggested Usage

3-10%

Appearance

Colorless, translucent solution

Solubility

Soluble in water

Long Term Storage

Pentapeptide-18 should be stored in the original sealed containers protected from light in a clean and cool place and is best kept in the refrigerator. Long term storage recommended between 39.2° – 44.6°F (4° - 7°C). If stored properly,it should have a shelf life of up to 24 months.

INCI

Water [Aqua] (and) Glycerin (and)Pentapeptide-18

Usage

Mix with Bellahut's gel base or cream base and a combination of our other premium peptides to create your own custom treatment that is tailored to your needs. For best results use at a 3% to 10% concentration, keep in mind 10% is the maximum suggested concentration level for this product.

This complex can create multiple products as below:

  • Wrinkle treatment product
  • Collagen boost product
  • Expression line treatment product

MSDS (Material Safety Data Sheet)

1. Product Identification

Product Name

Pentapeptide-18

INCI Name

Water[Aqua] (and) Glycerin (and)Pentapeptide-18

Composition/Information on Components

Gel containing a peptides

Hazardous Ingredients/Preservatives

None

2. Physical and Chemical Properties

Solubility in Water

Dispersible

pH

2-5

3. Stability and Reactivity

Chemical Stability

Stable

4. Handling and Storage

No particular precautions necessary. Long-term storage recommended between 4 and 7°C.

5. Accidental Release Measures

Absorb on appropriate material. Wash with water and detergent. Flush with water. Do not pour in pipes.

6. Exposure Controls & Personal Protection

Eye/ face Protection

Wear chemical goggles when there is a reasonable chance of eye contact.

7. Hazards Identification

Main Hazards

None

8. First Aid Measures

Eyes

Flush with water for 15 minutes, contact a physician if irritation persists

Inhalation

No data

Ingestion

Rinse one’s mouth. Give plenty of water.

9. Fire Fighting Measures

Extinguishing Media

Water, CO2

10. Toxicological Information

Patch test in humans (50%)

well tolerated

RIPT (50%)

non-sensitizing

HET CAM (50%)

slight irritant

Systemic Tests
Neutral red test

slight cytotoxicity

AMES test

non-mutagenic

11. Disposal Considerations

Destruction/ Elimination

water dilution

Soiled packaging

wash with water- recyclable container ( Caution: there may be local regulation to be observed )

Important Notice

This document is generated for the purpose of distributing health, safety, and environmental data. It is not a specification sheet nor should any displayed data be construed as a specification. The information on this MSDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, expressed or implied, regarding its correctness. Some information presented and conclusions drawn herein are from sources other than direct test data on the substance itself. The conditions or methods of handling, storage, use and disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss,damage, or expense arising out of or in any way connected with handling, storage, use or disposal of this product. If the product is used as a component in another product, this MSDS information may not be applicable.

Distributed by Bellahut California Made in U.S.A.