Helen Frankenthaler Foundation

Anxiety research neuropeptide

Neuropeptide EI (NEI)

Description

WARNING: This product is for research use only, not for human or veterinary use.

Neuropeptide EI (NEI) is an endogenous peptide fragment of rat prepro-melanin concentrating hormone (MCH) that is involved in hormone release, grooming behavior, and motor activity.

Related CAS #

No Data

Synonym

Neuropeptide EI (rat) (trifluoroacetate salt); NEI; Neuropeptide-Glutamic Acid-Isoleucine

IUPAC/Chemical Name

(4S,7S,10S,16S,19S)-19-amino-4-(((2S,5S,8S,11S,14S)-16-amino-1-((S)-2-(((2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-5-(4-aminobutyl)-2-benzyl-11-(hydroxymethyl)-8-methyl-1,4,7,10,13,16-hexaoxo-3,6,9,12-tetraazahexadecan-14-yl)carbamoyl)-16-((S)-sec-butyl)-7-(2-carboxyethyl)-10-(carboxymethyl)-6,9,12,15,18-pentaoxo-5,8,11,14,17-pentaazadocosanedioic acid--2,2,2-trifluoroacetic acid (1/1)

InChi Key

FABCGLFXCFXXIX-VXNMOIOASA-N

InChi Code

InChI=1S/C63H98N16O23.C2HF3O2/c1-6-31(3)50(52(67)91)77-61(100)43-17-13-25-79(43)63(102)41(26-34-14-9-8-10-15-34)75-55(94)36(16-11-12-24-64)71-53(92)33(5)69-60(99)42(30-80)76-58(97)39(27-44(66)81)74-57(96)38(20-23-48(87)88)72-56(95)37(19-22-47(85)86)73-59(98)40(28-49(89)90)70-45(82)29-68-62(101)51(32(4)7-2)78-54(93)35(65)18-21-46(83)84;3-2(4,5)1(6)7/h8-10,14-15,31-33,35-43,50-51,80H,6-7,11-13,16-30,64-65H2,1-5H3,(H2,66,81)(H2,67,91)(H,68,101)(H,69,99)(H,70,82)(H,71,92)(H,72,95)(H,73,98)(H,74,96)(H,75,94)(H,76,97)(H,77,100)(H,78,93)(H,83,84)(H,85,86)(H,87,88)(H,89,90);(H,6,7)/t31-,32-,33-,35-,36-,37-,38-,39-,40-,41-,42-,43-,50-,51-;/m0./s1

SMILES Code

CC[C@H](C)[C@@H](C(N)=O)NC([C@H]1N(C([C@H](CC2=CC=CC=C2)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC(CNC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)=O.O=C(O)C(F)(F)F

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction
Preparing Stock Solutions

The following data is based on the product molecular weight 1,561.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
1 mM1.15 mL5.76 mL11.51 mL
5 mM0.23 mL1.15 mL2.3 mL
10 mM0.12 mL0.58 mL1.15 mL
50 mM0.02 mL0.12 mL0.23 mL