H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bond)
Product Number: 4011941
CAS Number: 89213-87-6
Price range: $ 127.10 through $ 230.44
ANP/ANF is synthesized in cardiac myocytes and is primarily released in response to atrial wall stretching and intravascular volume expansion. The peptide signals via the guanylate cyclase-linked natriuretic peptide receptor A (NPR-A) and plays an important role in blood pressure regulation and blood volume homeostasis. ANP/ANF exerts vasodilatory, diuretic, natriuretic, anti-inflammatory, antifibrotic and antimitogenic effects. As BNP, ANP stimulates lipolysis in adipocytes. Millucci et al. studied the aggregation behavior of αANP, which may play a role in congestive heart failure.
Salt form: Trifluoroacetate
Molecular weight: 3080.49
Chemical Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃
Storage Temperature: < -15°C
Synonyms: Carperitide
One Letter code: SLRRSSCFGGRMDRIGAQSGLGCNSFRY
Source: Synthetic
Old Product Number: H-2095
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