Biotin-Galanin human molecular formula

Biotin Tripeptide-1

Item No. 27153

Technical Information

Formal Name: N-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxo pentyl]glycyl-L-histidyl-L-lysine

CAS Number: 299157-54-3

Synonyms:

• Biotinoyl Tripeptide-1
• Biotinyl-GHK
• Biotinyl-Gly-His-Lys

Molecular Formula: C24H38N8O6S

Formula Weight: 566.7

Purity: ≥95%

Formulation: A solid

Solubility: DMSO: 5mg/mL PBS (pH 7.2): 10mg/mL

SMILES: O=C(NCC(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CC1=CN=CN1)=O)CCCC[C@@H]2[C@@](NC(N3)=O)([H])[C@@]3([H])CS2

InChi Code: InChI=1S/C24H38N8O6S/c25-8-4-3-5-15(23(36)37)30-22(35)16(9-14-10-26-13-28-14)29-20(34)11-27-19(33)7-2-1-6-18-21-17(12-39-18)31-24(38)32-21/h10,13,15-18,21H,1-9,11-12,25H2,(H,26,28)(H,27,33)(H,29,34)(H,30,35)(H,36,37)(H2,31,32,38)/t15-,16-,17+,18+,21+/m0/s1

InChi Key: WCKVVODUWGBPQV-JDNULILRSA-N

Shipping & Storage Information

Storage: -20°C

Shipping: Wet ice in continental US; may vary elsewhere

Product Description

Biotin tripeptide-1 is an extracellular matrix (ECM) peptide that has been conjugated to biotin. It stimulates the production of collagen IV and laminin in dermal and epidermal cells ex vivo. Biotin tripeptide-1 localizes to the peri-pilial zone of isolated cultured human hair follicles, induces proliferation of keratinocytes, and increases hair growth by 58 and 121% compared with control follicles when used at concentrations of 2 and 5 ppm, respectively. It also prevents decreases in the collagen IV and laminin 5 bands of isolated cultured hair follicles.

WARNING This product is not for human or veterinary use.

References & Product Citations

Product Description References

1. Gorouhi, F., and Maibach, H.I. Role of topical peptides in preventing or treating aged skin. Int. J. Cosmet. Sci. 31(5), 327-345 (2009).

2. Lintner, K., and Maschamberlin, C. Formulations and method for treating baldness. (2006).