Catalog No. TP1705 Cas No. 100940-57-6
Gastrin I (1-14), human, is the 1-14 peptide fragment of human gastrin I, an endogenous gastrointestinal peptide hormone, and is the primary hormonal regulator of gastric acid secretion.
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The molecules in salt and non-salt forms exhibit the same activity, and they have consistent effects in biological experiments. Their activity and usage are identical. The only difference lies in their salt forms, which may result in variations in physical properties such as solubility. It is recommended to choose based on solubility and experimental requirements.
pIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).
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Effective dose 50 (ED50）refers to the dose of a drug that produces a specific effect in 50% of the population that has been administered that dose.
Half maximal effective concentratioin(EC50) refers to the concentration of a compound that achieves 50% of the maximum effect(inhibitory/stimulatory effect),after a specified exposure duration.
Purity:98.19% Appearance:Solid Color:White Contact us for more batch information
Description Gastrin I (1-14), human, is the 1-14 peptide fragment of human gastrin I, an endogenous gastrointestinal peptide hormone, and is the primary hormonal regulator of gastric acid secretion.
Molecular Weight 1705.73 Formula C 79 H 100 N 16 O 27 Cas No.100940-57-6 Smiles C([C@H](NC(=O)[C@H]1N(C(CNC(=O)[C@H]2NC(=O)CC2)=O)CCC1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(NCC(N[C@@H](CC=4C=5C(NC4)=CC=CC5)C(O)=O)=O)=O)=O)C)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CC(C)C)=O)C=6C=7C(NC6)=CC=CC7 Relative Density.1.432 g/cm3 (Predicted) Sequence{Glp}-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp Sequence Short{Glp}-GPWLEEEEEAYGW
Storage keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. Solubility Information H2O: Soluble
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method: For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH 2 O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation: Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation: 1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear. 2) Add 50 μL Tween 80 and mix well until fully clarified. 3) Add 450 μL Saline, PBS or ddH 2 O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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