Helen Frankenthaler Foundation

Bone formation therapy

Oxandrolone

Oxandrolone

Overview

Description A medication used to treat bone pain from osteoporosis and muscle loss that can happen after long-term treatment with steroid medications.

DrugBank ID DB00621

Modality Small Molecule

Patents 5

Indicated Conditions 4

Clinical Trials
PhaseCount
Phase 00
Phase 16
Phase 29
Phase 35
Phase 42
Therapeutic Categories
  • Androgens
Mechanism of Action
  • Androgen receptor Agonist

Identification

Summary

Oxandrolone is an androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis.

Brand Names

Oxandrin

Generic Name Oxandrolone

DrugBank Accession Number DB00621

Background

A synthetic hormone with anabolic and androgenic properties.

Modality Small Molecule

Groups Approved, Investigational

Structure

Weight Average: 306.4397

Monoisotopic: 306.219494826

Chemical Formula C 19 H 30 O 3

Synonyms
  • Ossandrolone
  • Oxandrolon
  • Oxandrolona
  • Oxandrolone
  • Oxandrolonum
External IDs
  • CB 8075
  • NSC-67068
  • SC 11585
  • SC-11585

Pharmacology

Indication

Use to promote weight gain after weight loss following extensive surgery.

Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Management ofPain••••••••••••
Management ofProtein catabolism••••••••••••
Associated Therapies
  • Weight Gain
Contraindications & Blackbox Warnings
Pharmacodynamics

Oxandrolone is an anabolic steroids indicated as adjunctive therapy to promote weight gain after weight loss following extensive surgery, chronic infections, or severe trauma, and in some patients who without definite pathophysiologic reasons fail to gai