Helen Frankenthaler Foundation

Cancer research biotin conjugate

Custom Protein-Biotin Conjugation Service

Custom Protein-Biotin Conjugation Service

Creative Biolabs offers specialized custom protein-biotin conjugation services to support a wide range of research and diagnostic applications.

Service Overview

Our bioconjugation platform provides tailored solutions for attaching biotin to various protein substrates, enabling applications in detection, purification, and immobilization.

Key Features

  • High conjugation efficiency and specificity
  • Preservation of protein activity and function
  • Flexible scale from research to production
  • Comprehensive quality control and analysis

Applications

Biotinylated proteins are essential tools in modern biotechnology.

Primary Uses
  • ELISA and immunoassay development
  • Affinity purification using streptavidin/avidin systems
  • Cell surface labeling and imaging
  • Protein-protein interaction studies

Our Process

We follow a systematic workflow to ensure successful conjugation.

Step-by-Step Workflow
  • Consultation and project design
  • Protein characterization and buffer optimization
  • Selection of biotinylation reagent and method
  • Conjugation reaction and purification
  • Quality analysis and validation
  • Final product delivery and documentation

Available Biotinylation Methods

We employ various chemical and enzymatic strategies to meet specific project requirements.

MethodDescriptionTypical Targets
Amine-reactiveTargets lysine residues and N-terminiSurface-exposed amines
Sulfhydryl-reactiveTargets cysteine residuesFree thiol groups
Carbohydrate-targetingOxidizes and labels glycansGlycosylation sites
EnzymaticUses specific ligases (e.g., BirA)Engineered peptide tags

Why Choose Our Service

Our expertise and commitment to quality make us a preferred partner.

  • Extensive experience with diverse protein types
  • Confidentiality and intellectual property protection
  • Fast turnaround times and dedicated project management
  • Technical support and consultation

Getting Started

Contact our scientific team to discuss your protein-biotin conjugation project requirements and receive a detailed proposal.