Synthetic Peptide
Order directly from
Abbiotec
938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA
Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: admin@frankenthalerfoundation.org
Website: https://www.frankenthalerfoundation.org
Alpha-conotoxin IMI is a 12-aa toxin isolated from the cone snail Conus imperialis venom. Alpha-conotoxin IMI is a potent blocker of the alpha/delta nicotinic acetylcholine channel receptors (nAChR) located on postsynaptic membranes. Alpha-conotoxin IMI inhibits in a voltage independent manner mammalian neuronal nAChRs (a3/b2 > a7 > a3/b4) and has no effect on nAChRs composed of a2/b2, a3/b2, a4/b2, a2/b4, a3/b4, or a4/b4 subunits. This toxin is highly active against the neuromuscular receptor in frog.
Format
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
Alpha-conotoxin ImI; alpha-CTx ImI
P50983
1347.58 g/mol
H-Gly-Cys-Cys-Ser-Asp-Pro-Arg-Cys-Ala-Trp-Arg-Cys-NH2 (Cys2-Cys8, Cys3-Cys12) or H-GCCSDPRCAWRC-NH2 (Cys2-Cys8, Cys3-Cys12)
C52H74N20O15S4
Purity > 95% by HPLC
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
For research use only, not for diagnostic or therapeutic procedures.
