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L-Carnosine Supplier | CAS 305-84-0 – Runtai Chemical

What is L-Carnosine?

L-Carnosine (β-Alanyl-L-Histidine) is a naturally occurring dipeptide composed of the amino acids beta-alanine and L-histidine. It is found in high concentrations in skeletal muscle, cardiac muscle, and brain tissue of vertebrates, where it plays a critical role in cellular defense and pH buffering.

L-Carnosine was first discovered in the early 20th century and has since been the subject of extensive scientific research. Its multifunctional bioactivity—spanning antioxidant, anti-glycation, metal-chelating, and pH-buffering mechanisms—makes it one of the most versatile naturally derived active ingredients in the specialty chemicals market.

Our L-Carnosine is synthesized under strictly controlled GMP conditions and undergoes rigorous QC testing at every production stage, suitable for pharmaceutical-grade, food-grade, and cosmetic applications, ensuring the highest standards for our global customers.

Runtai Chemical is a professional and reliable China manufacturer of L-Carnosine with CAS 305-84-0 with higher purity and lower price. If you are interested in our L-Carnosine, PLS free to contact us for a free sample!

Product Advantages

  • Powerful Antioxidant: L-Carnosine effectively scavenges reactive oxygen species (ROS) and free radicals, protecting cells from oxidative stress and damage.
  • Anti-Glycation Activity: Inhibits the formation of Advanced Glycation End-products (AGEs), which accumulate with age and are linked to neurodegenerative diseases, diabetes complications, and skin aging.
  • Metal Ion Chelation: Chelates transition metals such as copper, zinc, and iron, preventing metal-catalyzed oxidative reactions that damage proteins and nucleic acids.
  • pH Buffering in Muscle: Acts as a physiological pH buffer in skeletal muscle, delaying the onset of fatigue during high-intensity exercise by neutralizing lactic acid accumulation.
  • Neuroprotective Effects: Research supports L-Carnosine’s role in protecting neuronal cells from oxidative damage, with potential benefits in cognitive health and neurodegenerative conditions.
  • Skin Rejuvenation: Promotes collagen synthesis, inhibits cross-linking of skin proteins, and helps maintain youthful skin structure.

L-Carnosine Quick details

  • Chemical Name: L-Carnosine
  • CAS No.: 305-84-0
  • EINECS: 206-169-9
  • Molecular Formula: C9H14N4O3
  • Molecular weight: 226.23
  • Appearance: White of off-white powder
  • Assay: 99%
  • Synonyms: N-B-ALANYL-L-HISTIDINE; H-BETA-ALA-HIS-OH; L-IGNOTINE; L-BETA-ALANINE HISTIDINE; L-CARNOSINE; B-ALANYL-L-HISTIDINE; BETA-A-H; BETA-ALANYL-L-HISTIDINE

L-Carnosine Typical Properties

ItemSpecificationResults
AppearanceWhite of off-white powderConforms
HPLC IdentificationConsistent with the reference substance main peak retention timeConforms
Purity99.0%-101.0%99.85%
Heavy metal≤10ppmConforms
Specific rotation+20℃~+22℃+21.6℃
PH7.5-8.58.0
Loss on drying≤1.0%0.10%
Lead≤3ppmConforms
Arsenic≤1ppmConforms
Cadmium≤1ppmConforms
Mercury≤0.1ppmConforms
Residue on ignition≤0.1%0.01%
Hydrazine≤2ppmConforms
Melting point250.0℃-265.0℃255.0℃-256.6℃
Bulk density0.24g/ml
Tapped density0.51g/ml
L-Histidine≤0.3%0.05%
Total aerobes counts≤1000CFU/g42CFU/g
Mold &Yeast≤100CFU/gCFU/g
E.ColonegativeNot detectable
SalmonellanegativeNot detectable
ConclusionThe results conforms with enterprise standards

L-Carnosine Applications

  • Pharmaceutical & Nutraceuticals: Used as an active pharmaceutical ingredient in anti-aging drugs, neuroprotective formulations, eye drop solutions for cataracts (N-Acetylcarnosine), and gastrointestinal health products.
  • Sports Nutrition & Supplements: A popular ingredient in pre-workout formulas, endurance supplements, and muscle recovery products. Reduces exercise-induced oxidative stress and supports muscle buffering capacity.
  • Cosmetics & Skincare: Incorporated into premium anti-aging serums, creams, and skin treatments. Reduces glycation-induced skin damage, supports collagen integrity, and provides antioxidant protection against UV stress.
  • Veterinary & Pet Nutrition: Increasingly used in premium pet food supplements and veterinary applications to support healthy aging, joint health, and cognitive function in companion animals.

L-Carnosine Package&Storage

  • Package: 25kg/drum
  • Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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