H-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH₂
Product Number: 4027697
CAS Number: 161748-29-4
Price range: $ 451.33 through $ 1,782.77
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Glucagon-like peptide-1 (GLP-1) is efficiently degraded by the enzyme dipeptidyl peptidase IV (DPP IV), yielding the major metabolite GLP-1 (9-36) amide. GLP-1 (9-36) amide does not affect glucose disposal in mice either in the presence or absence of intact GLP-1 receptors or in the presence or absence of stimulated insulin levels. This suggests that the GLP-1 metabolite is not involved in the regulation of glucose homeostasis. Elahi et al. have shown that this GLP-1 metabolite acts as a weak insulinotropic agent and inhibits hepatic glucose production.
Salt form: Trifluoroacetate
Molecular weight: 3089.46
Chemical Formula: C₁₄₀H₂₁₄N₃₆O₄₃
Storage Temperature: < -15°C
Synonyms: Preproglucagon (100-127) amide (human, bovine, guinea pig, mouse, porcine, rat)
One Letter code: EGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH₂
Source: Synthetic
Old Product Number: H-4012
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