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Endozepine-derived neuropeptide supplier

Neuromedin B (porcine) | Bombesin Receptors

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Neuromedin B (porcine)

Cat. No. 1908

Discontinued Product

1908 has been discontinued.

Description

Mammalian bombesin-like peptide

Purity: ≥95% (HPLC)

Biological Activity

Neuromedin B (porcine) is a mammalian bombesin-like peptide and endogenous ligand for the neuromedin B receptor (IC 50 = 2 nM); first isolated from pig spinal cord. Regulates endocrine and exocrine secretion, smooth muscle contraction, blood pressure, feeding and cell growth.

Technical Data

PropertyValue
M. Wt1132.3
FormulaC 52 H 73 N 15 O 12 S
SequenceGNLWATGHFM (Modifications: Met-10 = C-terminal amide)
StorageStore at -20°C
Purity≥95% (HPLC)
CAS Number87096-84-2
PubChem ID6324606
InChI KeyYPFNACALNKVZNK-MFNIMNRCSA-N
Smiles[H]NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

  • Certificate of Analysis / Product Datasheet
  • Safety Datasheet

References

References are publications that support the biological activity of the product.

  • Minamino et al (1983) Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord. Biochem.Biophys.Res.Commun. 114 541 PMID:6882442
  • Ohki-Hamazaki et al (2000) Neuromedin B. Prog.Neurobiol. 62 297 PMID:10840151
  • Sainz et al (1998) Four amino acid residues are critical for high affinity binding of neuromedin B to the neuromedin B receptor. J.Biol.Chem. 273 15927 PMID:9632639
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Citations for Neuromedin B (porcine)

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Literature in this Area

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