Helen Frankenthaler Foundation

Galanin rat CAS 114547-31-8

Galanin (2-29) (rat) | CAS 141696-11-9

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Galanin (2-29) (rat)

Cat. No. 1451

Discontinued Product

1451 has been discontinued.

Description

Selective GAL 2 peptide agonist

Biological Activity

Peptide agonist for galanin receptors, showing selectivity for GAL 2 (K i values are 85, 1.9 and 12.6 nM at rat GAL 1, GAL 2 and GAL 3 receptors respectively).

Technical Data

PropertyValue
M. Wt3107.42
FormulaC 139 H 207 N 42 O 40
SequenceWTLNSAGYLLGPHAIDNHRSFSDKHGLT (Modifications: Thr-28 = C-terminal amide)
StorageDesiccate at -20°C
CAS Number141696-11-9
PubChem ID90469976
InChI KeyACSWKWWDLCUVJF-QTRPWDSUSA-N
Smiles[H]N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC=N1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

  • Certificate of Analysis / Product Datasheet
  • Safety Datasheet

References

References are publications that support the biological activity of the product.

  • Amiranoff et al (1989) Structural requirements for galanin action in the pancreatic β cell line rin m 5F. Eur.J.Pharmacol. 163 205 PMID:2472967
  • Wang et al (1997) Cloning and expressional characterization of a novel galanin receptor. J.Biol.Chem. 272 31949 PMID:9405385
  • Wang et al (1997) Molecular cloning and pharmacological characterization of a new galanin receptor subtype. Mol.Pharmacol. 52 337 PMID:9281594
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Keywords

Galanin (2-29) (rat), Galanin (2-29) (rat) supplier, Selective, GAL2, GalR2, peptide, agonists, Receptors, Galanin, 1451, Tocris Bioscience

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