Histatin-8 HIP peptide supplier

SARAFOTOXIN B

Product ID L8129-500UG

Description

A 21 amino-acids peptide with 2 disulfide bridges , synthetic, initially isolated from the venom of the Israeli mole viper Atractaspis engaddensis.

Biological Activity

Vasoconstrictor peptide; non-selective endothelin receptor agonist. Causes cardiac arrest probably as a result of coronary vasospasm (By similarity). Displays high agonistic activities towards endothelin-2 receptor (EDNRB) (displays affinity in the picomolar range) and endothelin-1 receptor (EDNRA) (lower affinities).

Packaging and Pricing

For quotation of big quantities, please Contact us

Safety Data Sheet

Available on request, please Contact us

Ref. SDS_L8129-500UG : unit price : free of charge

Product Specifications

Storage & Reconstitution

Recommandations Stable at room temperature, store preferably at 4°C

Savety Recommandations

Product code L8129-500UG

Product name SARAFOTOXIN B

References

• 1. Aimoto et al (1990) Studies on the disulfide bridges of sarafotoxins. Chemical synthesis of sarafotoxin S6B and its homologue with different disulfide bridges. Biochem.Int. ;
• 2. Bax et al (1994) Different endothelin receptors involved in endothelin-1- and sarafotoxin S6B-induced contractions of the human isolated coronary artery. Br.J.Pharmacol. ;
• 3. Devadason and Henry (1997) Comparison of the contractile effects and binding kinetics of endothelin-1 and sarafotoxin S6b in rat isolated renal artery. Br.J.Pharmacol.

Product code L8129-500UG

Product name SARAFOTOXIN B

External Links

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Biomedical Citations From PubMed

Toxicology Citations From PubMed

PubChem CID

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