This gene encodes neuropeptides involved in analgesia, cardiovascular regulation, neuroendocrine function and opiate addiction. The encoded protein is a preproprotein that undergoes further processing to generate multiple amidated peptides. [provided by RefSeq, Jul 2015]
There are 1 transcripts and 1 protein isoforms for Npff gene.
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* This data comes from NCBI.
Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels.
Neuron
2000
16.2
Gene for pain modulatory neuropeptide NPFF: induction in spinal cord by noxious stimuli.
Molecular pharmacology
1999
3.6