Found 8 products.
CAS: 2381089-83-2
Retatrutide (LY3437943) is a triple agonist of GCGR, GIPR and GLP-1R that can be used to study obesity.
Estimated delivery time: ~13 days
Estimated delivery time: ~14 days
Retatrutide is a 39 amino acid single peptide with triple agonist activity at the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). The backbone is conjugated to a C20 fatty diacid moiety at position 17. Retatrutide has a Glucose-dependent insulinotropic polypeptide (GIP) peptide backbone, which then contains three non-coded amino acids. Aib2 (α-amino isobutyric acid) residues at positions 2 and 20 provide stability against Dipeptidyl Peptidase 4 (DPP4) cleavage and contribute to GIP activity. αMeL13 (α-methyl-L-leucine)at position 20 also contributes to GIP and glucagon activity. Retatrutide can be used for the research of obesity obesity, diabetes, and fatty liver disease. It is a works in three ways: stimulating insulin release, suppressing appetite, and promoting fat breakdown.
Estimated delivery time: ~24 days
GLP-1, GIP, and GCGR2 mimic; Obesity research
Sodium salt; GLP-1, GIP, and GCGR2 mimic; Obesity research
Acetate salt; GLP-1, GIP, and GCGR2 mimic; Obesity research
Estimated delivery time: ~83 days
Estimated delivery time: ~92 days