Helen Frankenthaler Foundation

Neuromedin B-30 peptide

FLP-20 neuropeptides: AMMRFa, AVFRMa, SVFRLa

acetyl tetrapeptide 2 lab product clean

FLP-20 neuropeptides: AMMRFa, AVFRMa, SVFRLa

Not For Human Use, Lab Use Only.

Cat.#: 318734

Size

  • 5.0 mg
  • 5.0 mg (TFA removed)
  • 20.0 mg
  • 20.0 mg (TFA removed)

Special Price 220.00 USD

Availability:1-2 weeks

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Product Information

AttributeDetails
Product NameFLP-20 neuropeptides：AMMRFa, AVFRMa, SVFRLa
DocumentsHandling and Storage of Synthetic Peptides, Material Safety Data Sheets (MSDS)
Sequence ShorteningAMMRF-NH2, AVFRM-NH2, SVFRL-NH2
Length (aa)5
Peptide Purity (HPLC)95.8%
Molecular FormulaC 28 H 47 N 9 O 5 S 2
Molecular Weight653.86
SourceSynthetic
FormPowder
DescriptionAll three peptides encoded by the flp-20 gene (AMMRFa, AVFRMa, SVFRLa) were able to activate FRPR-3 receptor, the FMRFamide-like peptide GPCR FRPR-3, with EC50 values in the low nanomolar range. AMMRFa refers to AMMRF-NH2(C 28 H 47 N 9 O 5 S 2, MW: 653.86); AVFRMa = AVFRM-NH2(C 28 H 47 N 9 O 5 S, MW: 621.79); SVFRLa = SVFRL-NH2(C 29 H 49 N 9 O 6, MW: 619.75). These FLP-20 peptides function as an afferent arousal signal that conveys mechanosensory information to central neurons that modulate arousal and other behavioral states.
Storage GuidelinesNormally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C.
ReferencesChew et al., An Afferent Neuropeptide System Transmits Mechanosensory Signals Triggering Sensitization and Arousal in C. elegans, Neuron (2018), https://www.frankenthalerfoundation.org
About TFA salt

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

Molar Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Dilution Calculator

Concentration (stock) × Volume (stock) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C 1 V 1 = C 2 V 2

Percent Concentration Calculator

This equation is commonly abbreviated as: %(w/v) = Weight of solute(g) / Volume of solution(mL) × 100%

Related Products / Services

  • Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
  • Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.
  • Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2 H, 15 N, and 13 C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"