Neurotensin is a tridecapeptide that functions as a neurotransmitter and neuromodulator in the central nervous system and as a hormone in the periphery. It is involved in various physiological processes, including pain modulation, dopamine transmission, and the regulation of gastrointestinal motility.
The amino acid sequence for Neurotensin is: pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu.
Neurotensin exerts its effects by binding to specific G protein-coupled receptors, primarily NTS1, NTS2, and NTS3. It is known to induce hypotension, hyperglycemia, and hypothermia, and to modulate dopaminergic pathways.
This peptide is widely used in neuroscience, pharmacology, and cell biology research to study its receptor interactions, signaling pathways, and potential therapeutic applications for disorders such as schizophrenia, pain, and cancer.
For long-term storage, it is recommended to keep the lyophilized peptide at -20°C. Reconstitute in sterile distilled water or buffer immediately before use.
GenScript offers a range of related peptides and services, including custom peptide synthesis, peptide libraries, and analytical services.
