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NMUR2 Gene - GeneCards | NMUR2 Protein

NMUR2 Gene

This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008]

Aliases for NMUR2 Gene

  • GeneCards Symbol: NMUR2
  • Neuromedin U Receptor 2
  • NMU2R
  • G-Protein Coupled Receptor TGR-1
  • G-Protein Coupled Receptor FM-4
  • Neuromedin-U Receptor 2
  • NMU-R2
  • TGR1
  • Growth Hormone Secretagogue Receptor Family, Member 4
  • TGR-1
  • FM-4
  • FM4
Previous HGNC Symbols for NMUR2 Gene
  • NMU2R
Previous GeneCards Identifiers for NMUR2 Gene
  • GC05M151801
  • GC05M151751
  • GC05M146910

This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008]

Neuromedin U (NMU) receptors are a group of Gq/11-protein-coupled receptors that are currently divided into two subtypes: NMU1 and NMU2. The two subtypes have distinct tissue distributions: NMU1 is expressed in the periphery, whilst NMU2 is expressed in the CNS.

  • HGNC (16454)
  • NCBI Gene (56923)
  • Ensembl (ENSG00000132911)
  • OMIM® (605108)
  • UniProtKB/Swiss-Prot (Q9GZQ4)
  • Open Targets Platform(ENSG00000132911)
  • Alliance of Genome Resources
  • Search for NMUR2 at DataMed
  • Search for NMUR2 at HumanCyc

No data available for CIViC Summary , Rfam classification and piRNA Summary for NMUR2 Gene

Promoters and enhancers for NMUR2 Gene

GeneHancer (GH) IdentifierGH TypeGH ScoreGH SourcesGene Association ScoreTotal ScoreTSS distance (kb)Number of Genes AwaySize (kb)Transcription Factor Binding SitesGene Targets
GH05J152405Promoter0.5EPDnew, Ensembl324.30162.15+28.000.2-5 genes NMUR2 ...
GH05J152349Enhancer0.8RefSeq, Ensembl20.7017.51+83.430.412 TFs CTCF ZNF654 ...5 genes NMUR2 ...
GH05J152456Enhancer0.6RefSeq24.2015.55-23.510.38 TFs BATF IKZF1 ...4 genes NMUR2 ...
GH05J152455Enhancer0.3RefSeq24.206.92-21.910.2-4 genes NMUR2 ...