NPR‑A receptor agonist

Adrenergic beta-1 Receptor Antagonists | DrugBank

Name Adrenergic beta-1 Receptor Antagonists

Accession Number DBCAT000458

Drugs that bind to and block the activation of ADRENERGIC BETA-1 RECEPTORS.

Drug	Drug Description
Acebutolol	A selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults.
Atenolol	A synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients.
Betaxolol	A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically).
Bevantolol	For the treatment of angina pectoris and hypertension.
Bisoprolol	A beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension.
Carvedilol	A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
Celiprolol	A beta-blocker for the management of hypertension and angina pectoris.
Esmolol	A cardioselective beta-adrenergic blocker used for the short-term control of ventricular rate and heart rate in various types of tachycardia, including perioperative tachycardia and hypertension.
Metoprolol	A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction.
Practolol	Used in the emergency treatment of cardiac arrhythmias.

Drug	Target	Type
Acebutolol	ATP-dependent translocase ABCB1	transporter
Acebutolol	Beta-2 adrenergic receptor	target
Acebutolol	Cytochrome P450 2D6	enzyme
Acebutolol	Beta-1 adrenergic receptor	target
Atenolol	Beta-1 adrenergic receptor	target
Atenolol	Beta-2 adrenergic receptor	target
Atenolol	Cytochrome P450 2D6	enzyme
Atenolol	Bile salt export pump	transporter
Atenolol	Albumin	carrier
Betaxolol	Beta-1 adrenergic receptor	target
Betaxolol	Beta-2 adrenergic receptor	target
Betaxolol	Cytochrome P450 1A2	enzyme
Betaxolol	Cytochrome P450 2D6	enzyme
Bevantolol	Beta-1 adrenergic receptor	target
Bevantolol	D(2) dopamine receptor	target
Bevantolol	Cytochrome P450 2D6	enzyme
Bevantolol	Alpha-1A adrenergic receptor	target
Bevantolol	Beta-2 adrenergic receptor	target
Bisoprolol	Beta-1 adrenergic receptor	target
Bisoprolol	Beta-2 adrenergic receptor	target
Bisoprolol	Cytochrome P450 3A4	enzyme
Bisoprolol	ATP-dependent translocase ABCB1	transporter
Carvedilol	Alpha-2A adrenergic receptor	target
Carvedilol	E-selectin	target
Carvedilol	Hypoxia-inducible factor 1-alpha	target
Carvedilol	Inward rectifier potassium channel 4	target
Carvedilol	Inward rectifier potassium channel 2	target
Carvedilol	UDP-glucuronosyltransferase 1A1	enzyme
Carvedilol	Albumin	carrier
Carvedilol	UDP-glucuronosyltransferase 2B4	enzyme
Carvedilol	UDP-glucuronosyltransferase 2B7	enzyme
Carvedilol	Alpha-2B adrenergic receptor	target
Carvedilol	Alpha-2C adrenergic receptor	target
Carvedilol	Alpha-1B adrenergic receptor	target