Helen Frankenthaler Foundation

Palmitoyl Peptides

Palmitoyl tetrapeptide-20

Palmitoyl tetrapeptide-20

Palmitoyl tetrapeptide-20 (Synonyms: PTP20) is a biomimetic peptide that is an agonist for α-MSH. Products are for research use only. Not for human use. We do not sell to patients.

Description of Palmitoyl tetrapeptide-20

Palmitoyl tetrapeptide-20 (PTP20) is a biomimetic peptide that is an agonist for α-MSH. Palmitoyl tetrapeptide-20 can protect follicular melanocytes and activate melanogenesis by enhancing catalase expression.

References:

  • Almeida Scalvino S, et al. Efficacy of an agonist of α-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation. Int J Cosmet Sci. 2018;40(5):516-524.

Chemical Properties of Palmitoyl tetrapeptide-20

PropertyValue
Cas No.SDF
SynonymsPTP20
FormulaC38 H70 N6 O8
Molecular Weight739
SolubilityDMSO: 28.57 mg/mL (38.66 mM; adjust pH to 4 with 1 M HCL)
StorageSealed storage, away from moisture

General tips: Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing. Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. Shipping Condition: Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Palmitoyl tetrapeptide-20
Concentration1 mg5 mg10 mg
1 mM1.3532 mL6.7659 mL13.5318 mL
5 mM270.6 µL1.3532 mL2.7064 mL
10 mM135.3 µL676.6 µL1.3532 mL
In vivo Formulation Calculator (Clear solution) of Palmitoyl tetrapeptide-20

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

  • Dosage: mg/kg
  • Average weight of animals: g
  • Dosing volume per animal: µL
  • Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH2O

% DMSO + %

Calculation results:

  • Working concentration: mg/ml;
  • Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO (Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.)
  • Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80, mix and clarify, next add µL ddH2O, mix and clarify.
  • Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL Corn oil, mix and clarify.

Note:

  • Please make sure the liquid is clear before adding the next solvent.
  • Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
  • All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

View current batch: Purity: >99.00%

  • COA (Certificate Of Analysis)
  • SDS (Safety Data Sheet)