Helen Frankenthaler Foundation

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Pharmokinetics of Exemestane - Training / Bodybuilding - T NATION

Pharmokinetics of Exemestane

Just discovered this article: https://www.frankenthalerfoundation.org

Exemestane is a steroidal irreversible aromatase blocker. It says irreversible but in this context I don’t really understand what that would entail (as in more receptors are created vs. take it for 10 days and you are done for life). Interesting read. 25mg ED (half life 8 hours) would be the dosing requirements.

User Discussion

Raw_Power

Thanks for posting the link for this article. This is added information to what I already knew since beginning this drug for high estradiol due to TRT three weeks ago.

themonthofjun

E2=? just curious for a range.

Raw_Power

My E2 was 34 pg/mL.

Of course, that was in normal ranges according to LabCorp. (I did my blood test through Life Extension Foundation). The problem was I had all the symptoms of high E even though the numbers were in normal range. An LFE doctor told me that I needed to get that down. I needed to cut the E levels in half is what it came down to. Being on a low dose of TRT (Testim 5g) did increase free and total T, but it also created the higher E and the “parade was rained on”.

Once again, doctors need to treat the symptoms instead of the numbers especially in this case. My doctor insisted that I go on TRT (my total T in the beginning was 135). Now that my E levels have gone up and I had the symptoms my doctor doesn’t want to discuss the issue and when I asked about checking my E levels with a blood test he looked at me like I was crazy and walked out of the examining room. Now I just do my own blood tests and get my medicine elsewhere.

themonthofjun

So you had an LFE doc and the doc that prescribed TRT? And your doc walked out on you? Your doc must be a super douchebag.

I should then be thankful I have a doc that lets me get away with that stuff.

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