Purity: 95%
CAT.NO: P300223
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Product Name: Pentapeptide-25
Storage: Keep in dark and cool dry place -5~8 degree Celsius
Sequence: Lys-Val-Arg-Leu-GIn
Pentapeptide-25 is a biomimetic five–amino acid peptide designed to support visible skin revitalization, firmness, and overall radiance. Known for its ability to enhance cellular communication, it helps promote healthier skin turnover, improved elasticity, and a smoother, more refined texture. In cosmetic research, Pentapeptide-25 is valued for reducing the appearance of fine lines and restoring vitality to dull, stressed, or aging skin. Its excellent formulation stability and compatibility with serums, creams, and advanced anti-aging treatments make it ideal for products targeting improved skin density, suppleness, and a youthful, refreshed complexion.
Pentapeptide-25 (also known as UCPeptide? V) is a synthetic body-contouring and anti-cellulite peptide. It is a five–amino-acid sequence (Lys–Val–Arg–Leu–Gln) designed to mimic part of the sequence of uncoupling proteins (UCPs) found in mitochondria, especially in adipocytes.
UCPs are mitochondrial transport proteins that regulate how efficiently cells convert nutrients into ATP versus heat. In adipose tissue, they play an important role in energy expenditure and triglyceride metabolism, and have been explored as targets in obesity and metabolic disease research. Pentapeptide-25 borrows this biology and repackages it into a topical, cosmetic peptide for localized fat and cellulite care.
Formulator and technical sources describe Pentapeptide-25 as a UCP-mimetic peptide that acts on subcutaneous fat and cellulite when applied to the skin.
Key mechanistic themes:
The peptide “retraces” a sequence from the UCP family and is designed to emulate aspects of UCP activity in adipocytes. By influencing pathways that regulate triglyceride storage and energy dissipation, it aims to shift fat cells away from storage mode and towards increased utilization of stored lipids.
Supplier and ingredient-guide descriptions consistently state that Pentapeptide-25 limits lipid storage, leading to:
By shrinking and “emptying out” adipocytes in the treated area, the peptide supports visible slimming and smoother contours.
Excess triglyceride storage in localized areas (thighs, buttocks, abdomen, arms) enlarges fat lobules, pushes against the dermis, and accentuates fibrous septa — the classic “orange peel” look. Pentapeptide-25 is reported to reduce fat and cellulite formation in the skin, allowing the surface to gradually regain a more even appearance.
Some marketing material also highlights secondary benefits such as skin repair and anti-allergy potential, but the core science and positioning remain focused on slimming and cellulite reduction.
Within the cosmetic peptide “family tree,” Pentapeptide-25 belongs to the slimming / anti-cellulite peptides, alongside actives like Tripeptide-41 and Acetyl Hexapeptide-39 that act on adipocyte differentiation, lipid accumulation, or fat-cell metabolism.
Distinctive features:
Reviews of cosmetic peptides note growing interest in body-care actives that go beyond caffeine by acting on adipogenesis, lipid metabolism, and ECM remodeling, and Pentapeptide-25 fits neatly into this advanced, mechanism-based category.
Public, peer-reviewed in vitro data specifically on Pentapeptide-25 are limited; most information comes from supplier studies, patents, and technical ingredient guides. Collectively they support the following picture:
Cell / biochemical models
Body and skincare context
These data are typical of cosmetic-grade evidence (rather than pharmaceutical clinical trials), so any promises should stay clearly within appearance-focused, non-medical claims.
Pentapeptide-25 is supplied as a high-purity synthetic peptide (often ≥98% by HPLC) for use as a cosmetic raw material.
Key practical points:
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Category: Cosmetic Peptides
