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Catalog No. T0624 Cas No. 1137-42-4
Alias 4-Benzoylphenol
4-Hydroxybenzophenone (4-Benzoylphenol) is used as an intermediate of infertility drugs Clomifene.
Other Forms of 4-Hydroxybenzophenone:
4-Hydroxybenzophenone (Standard) TMSM-0286 1137-42-4
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Purity:99.86%
Catalog No. T0624 Alias 4-Benzoylphenol Cas No. 1137-42-4
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In Stock Estimated shipping date USA Warehouse 1-2 days Global Warehouse 5-7 days
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Q How much inhibitor should be added in cell experiments?
A It is recommended to refer to literatures of experiments conducted using the same model. In addition, it is also necessary to determine the optimal working concentration (concentration gradient) through pre-experiments by constructing a dose-response curve. Similarly, the optimal incubation time (time gradient) should be determined through a time-course experiment. Moreover, the amount of inhibitor used is influenced by various factors, including the accessibility of the target, cell permeability, incubation time, cell type, and others. We recommend determining the initial concentration of the inhibitor by referring to the literatures. If the Ki or IC50 are reported, it is recommended to start with 5-10 times their reported values to achieve the optimal inhibition of enzyme activity. If the Ki or IC50 are unknown, the inhibitor concentrations should be tested, and the Ki value can be calculated using Michaelis-Menten kinetics. Typically, the solvent used for dissolving the inhibitor is used as a control to eliminate the non-specific effects of the solvent.
Q Can inhibitors be used for animal experiments?
A Yes, our inhibitors can be used for animal/in vivo experiments. However, some compounds may not have literature supporting their use in animal experiments. In such cases, we cannot guarantee efficacy.
Q How to set the concentration of stock solution?
A The concentration of stock solution should be lower than the solubility provided on the official website. Within this range, the concentration of stock solution should be set based on that of working solution. For cell experiments, it is recommended to set the stock solution concentration at least 1000 times higher than that of working solution.
Q Can inhibitors be used for cell experiments?
A Yes, our inhibitors can be used for cell/in vitro experiments. However, some compounds may not have literature supporting their use in cell experiments. In such cases, we cannot guarantee efficacy.
Q Does the product need to be protected from light?
A Generally, for molecules that require light-protected storage, we will ship them in amber glass bottles.
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Appearance: Solid
Color: White
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DataSheet SDS COA LCMS HNMR
4-Hydroxybenzophenone AI Summary
4-Hydroxybenzophenone exhibits inhibitory activity against the recombinant rat androgen receptor with an IC50 of 181970.09 nM, suggesting potential anti-androgen properties. Additionally, 4-Hydroxybenzophenone shows leishmanicidal activity against the promastigote form of Leishmania a...More
Note: Summary generated by AI. Data source: ChEMBL
Description 4-Hydroxybenzophenone (4-Benzoylphenol) is used as an intermediate of infertility drugs Clomifene. Synonyms 4-Benzoylphenol
Molecular Weight 198.22 Formula C 13 H 10 O 2 Cas No.1137-42-4 Smiles OC1=CC=C(C=C1)C(=O)C1=CC=CC=C1 Relative Density.1.1184 g/cm3 (Estimated)
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. Solubility Information DMSO: 55 mg/mL (277.47 mM), Sonication is recommended. In Vivo Formulation 10% DMSO+40% PEG300+5% Tween-80+45% Saline: 5 mg/mL (25.22 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH 2 O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation: Dissolve 2 mg of the compound in 100 μL DMSO
