Tryptamine Therapeutics Limited is a clinical-stage biotechnology company focused on bringing transformative medicine with known safety profiles to diseases with no effective first-line treatments.
Tryptamine Therapeutics intends to accomplish this through the development of an IV infusion of psilocin (the active metabolite of psilocybin) which addresses many of the current limitations associated with orally administered psilocybin used by the majority of competitors in the field.
Tryp’s lead programs are designed to address neuropsychiatric disorders through the therapeutic dosing of synthetic psilocybin and IV infused psilocin in conjunction with psychotherapy.
With a focus on:
We are pioneering proprietary formulations for synthetic psilocybin and psilocin and novel techniques for its manufacture. We are developing dosing and delivery methods for psychedelics to reduce the time spent by patients in the psychedelic state, thereby improving their experience.
We are pursuing global patents at every opportunity, with a foundational provisional patent application already filed and many more to come.
Our senior leaders have proven abilities to build and scale across a variety of relevant categories. Our management team has an innate ability to create and nurture collaborations with the best scientific talent from leading universities and research institutions around the world.
Millions of people suffer from health conditions like chronic pain, for which few or no effective treatment options currently exist. Each one of these conditions is a humanitarian need — and an unaddressed market opportunity. Our pharmaceutical focus on psilocybin has the potential to transform the treatment of chronic pain and other indications, and relieve the suffering of millions of patients.
“By allowing rapid initiation and termination of the psychedelic experience, as well as providing highly refined control over the depth and duration of that experience, I believe TRP-8803 has a very strong potential to shift the treatment paradigm for fibromyalgia and binge eating disorder, as well as certain types of depression, pain and obsessive-compulsive disorders.”
— Robin Carhart-Harris, Ph.D. Chairman, Scientific Advisory Board
Daniel Tillett
Dr Daniel Tillett is the founder and CEO of Nucleics, a private Australian biotechnology company producing and selling world leading DNA sequencing software to the Genomics industry. Nucleics SAAS (software as a service) genomics tools are in use in more than 30 countries and at over 250 companies and institutions. Dr Tillett is also Managing Director & Chief Executive Officer of Race Oncology Limited (ASX: RAC), a clinical stage biopharmaceutical company with a dedicated mission to be at the heart of cancer care.
Previously, he was a Senior Lecturer within the School of Pharmacy at La Trobe University where he taught and researched in the areas of pharmacy, phage therapy, microbiology, bioinformatics and cancer.
Dr Tillett has extensive commercial experience over the last 20 years in the biotech industry in project management, sales and marketing, IP management, fundraising and start-up investing.
Dr Tillett has a PhD from the University of New South Wales in Molecular Genetics and Biochemistry. He has more than 40 scientific publications and granted patents in molecular biology, microbiology, genetics and biochemistry.
Herwig Janssen
Mr Janssen is an internationally renowned healthcare and pharmaceutical executive. Most recently, he served as Vice President for Licensing & Acquisitions (Emerging Markets) at J&J Innovative Medicine (formerly Janssen Pharmaceuticals), a subsidiary of multinational conglomerate Johnson & Johnson for nearly three decades.
Mr Janssen brings more than 40 years of sector experience, where he has led business development activities for J&J across global emerging markets with a demonstrated track record in licensing, technology transfers and M&A. As a member of the Janssen family, he has a long association with J&J in connection with the strategic acquisition of Janssen Pharmaceuticals.
His other roles within the group include VP of Business Development in the US, which provided him with a strong understanding of J&J, while also demonstrating his ability to effectively execute a number of diverse deals and strategic agreements. Following this, Mr Janssen undertook multiple senior positions in R&D, international marketing, sales and business development across J&J’s consumer and pharmaceutical businesses.
Mr Janssen’s ability has been recognised through the James E Burke Award, which is the group’s highest internal honour and is awarded for outstanding leadership and integrity, while delivering exceptional business impact.
Hamish George
Mr George is a Director at Bio101 Financial Advisory (‘Bio101’), a financial services firm providing outsourced CFO, taxation and company secretarial solutions to the biotechnology and healthcare sector. He has over 10 years of finance and commercial experience working with public and private companies in Australia and abroad. Mr George currently serves as CFO and Company Secretary for several ASX-listed, private companies and not-for-profits.
He holds a Bachelor of Commerce from the University of Melbourne, a Masters Degree in Professional Accounting from RMIT, a Certificate in Governance Practice from the Governance Institute of Australia and is a qualified Chartered Accountant.
Philippa Hay
Professor Philippa Hay is a renowned academic psychiatrist with international recognition for her research on eating disorders and obesity. With over 500 scientific papers and significant contributions to clinical practice and treatment guidelines, she has influenced national and international standards.
Notably, she led the development of the Royal Australian and New Zealand College of Psychiatrists’ national guidelines and the EDP framework for Medicare-supported recovery in Australia. Awarded the ANZ Academy for Eating Disorders Lifetime Leadership Award and the RANZCP Senior Research Award, she is also the founding Editor-in-Chief of the Journal of Eating Disorders and a past-President of the Australian Academy for Eating Disorders.
Her current research includes clinical trials for anorexia nervosa, public health interventions, and the exploration of psychedelics in treatment. She serves as a principal reviewer for the Cochrane Library and frequently contributes to leading journals and publications.
David Castle
Professor David Castle is a distinguished psychiatric scholar, who most recently was appointed by the Tasmanian Government as Professor of Psychiatry at the University of Tasmania’s Centre for Mental Health Service Innovation, launched in partnership with the Tasmanian Department of Health.
Previously, he served as the Inaugural Scientific Director at the Centre for Complex Interventions and the Centre for Addictions and Mental Health at the University of Toronto, and as Professor of Psychiatry at the University of Melbourne. With a focus on mental health conditions such as schizophrenia, bipolar disorder, and OCD, he is known for his research on psychedelic treatments and body dysmorphic disorder.
Professor Castle has published over 900 works, reviews for numerous scientific journals, and has a strong track record in securing significant research funding.
William Schmidt, PhD
William Schmidt, PhD is a Scientific Advisor to Tryp Therapeutics.
Dr. Schmidt serves as an expert on pain medicine pharmaceutical development with pharmaceutical and biotech companies throughout North America, Europe, Asia, Latin America and Australia. He currently sits on the Scientific or Medical Advisory Boards of five biotech companies. Dr. Schmidt has received many awards throughout his career including the John J. Bonica award for the development of new analgesics and for his sustained contributions to the educational efforts of the Eastern Pain Association in 2014. He joined DuPont Pharmaceuticals where he helped to develop nalbuphine (Nubain®), naltrexone (Trexan®, ReVia®
