Urocortin rat peptide

Urocortin (human)

Cat. No. 1604

Description: Endogenous CRF agonist

Purity: ≥95% (HPLC)

Biological Activity

Urocortin (human) is an endogenous CRF agonist. K i values are 0.4, 0.3 and 0.5 nM for hCRF 1, rCRF 2 α and mCRF 2 β respectively.

Licensing Information

Sold with the permission of the SALK Institute

Technical Data

M. Wt 4696.29

Formula C 204 H 337 N 63 O 64

Sequence DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV (Modifications: Val-40 = C-terminal amide)

Storage Store at -20°C

Purity≥95% (HPLC)

CAS Number 176591-49-4

PubChem ID 24868180

InChI Key BIIOOWPFSOAZSO-WODJFTBTSA-N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet

Safety Datasheet

References

References are publications that support the biological activity of the product.

• Perrin and Vale (1999) Corticotropin releasing factor receptors and their ligand family. Ann.N.Y.Acad.Sci. 885 312 PMID:10816663
• Reul and Holsboer (2002) Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. Curr.Opin.Pharmacol. 2 23 PMID:11786305
• Skelton et al (2000) The neurobiology of urocortin. Regul.Pept. 93 85 PMID:11033056

If you know of a relevant reference for Urocortin (human), please let us know.

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