Vasopressin receptor detection probe

Research Citations

This section lists key scientific publications related to Pentagastrin, covering its role in acid secretion studies, calcitonin stimulation tests, and investigations as a potential antiviral agent, including against African Swine Fever Virus (ASFV).

Recent Studies (2024-2021)

• Namikawa K, Björnsson ES. Rebound Acid Hypersecretion after Withdrawal of Long-Term Proton Pump Inhibitor (PPI) Treatment-Are PPIs Addictive? Int J Mol Sci. 2024 May 17;25(10):5459. doi: 10.3390/ijms25105459. PMID: 38791497; PMCID: PMC11122117.
• Choi J, Lee H, Cho S, Choi Y, Pham TX, Huynh TTX, Lim YS, Hwang SB. Polygalic acid inhibits african swine fever virus polymerase activity: findings from machine learning and in vitro testing. J Comput Aided Mol Des. 2023 Sep;37(9):453-461. doi: 10.1007/s10822-023-00520-6. Epub 2023 Jul 15. PMID: 37452977.
• Yang K, Jin H, Gao X, Wang GC, Zhang GQ. Elucidating the molecular determinants in the process of gastrin C-terminal pentapeptide amide end activating cholecystokinin 2 receptor by Gaussian accelerated molecular dynamics simulations. Front Pharmacol. 2023 Jan 23;13:1054575. doi: 10.3389/fphar.2022.1054575. PMID: 36756145; PMCID: PMC9899899.
• Aksoydan B, Durdagi S. Virtual drug repurposing study for the CGRPR identifies pentagastrin and leuprorelin as putative candidates. J Mol Graph Model. 2022 Nov;116:108254. doi: 10.1016/j.jmgm.2022.108254. Epub 2022 Jun 18. PMID: 35803082.
• Dubey A, Saini S, Sharma V, Malik H, Kumar D, De AK, Bhattacharya D, Malakar D. Deducing Insulin-Producing Cells from Goat Adipose Tissue-Derived Mesenchymal Stem Cells. Cell Reprogram. 2022 Aug;24(4):195-203. doi: 10.1089/cell.2022.0029. Epub 2022 Jul 5. PMID: 35787695.
• Kiriakopoulos A, Giannakis P, Menenakos E. Calcitonin: current concepts and differential diagnosis. Ther Adv Endocrinol Metab. 2022 May 21;13:20420158253577914. doi: 10.1177/20420158253577914. PMID: 35614985; PMCID: PMC9125613.
• Choi J, Tark D, Lim YS, Hwang SB. Identification of African Swine Fever Virus Inhibitors through High Performance Virtual Screening Using Machine Learning. Int J Mol Sci. 2021 Dec 14;22(24):13414. doi: 10.3390/ijms222413414. PMID: 34948216; PMCID: PMC8703626.
• Choi J, Yun JS, Song H, Shin YK, Kang YH, Munashingha PR, Yoon J, Kim NH, Kim HS, Yook JI, Tark D, Lim YS, Hwang SB. Prediction of African Swine Fever Virus Inhibitors by Molecular Docking-Driven Machine Learning Models. Molecules. 2021 Jun 11;26(12):3592. doi: 10.3390/molecules26123592. PMID: 34208385; PMCID: PMC8231271.
• Băetu M, Olariu CA, Moldoveanu G, Corneci C, Badiu C. Calcitonin Stimulation Tests: Rationale, Technical Issues and Side Effects: A Review. Horm Metab Res. 2021 Jun;53(6):355-363. doi: 10.1055/a-1487-6449. Epub 2021 Jun 21. PMID: 34154026.
• Xie Y, Liu H, Chen X, Xing J. The Effect of Gastric pH on the Pharmacokinetics-pharmacodynamics of Naphthoquine in Rodents, as well as in Human Predicted Using a PBPK Model. Curr Drug Metab. 2021;22(5):363-371. doi: 10.2174/1582535779166210129102411. PMID: 33511926.
• Shah J, Bush N, Rajan K, Nain CK, Singh K, Kochhar R. Gastric secretion in patients with caustic ingestion: A prospective study. Indian J Gastroenterol. 2021 Feb;40(1):50-55. doi: 10.1007/s12664-020-01116-w. Epub 2021 Jan 8. PMID: 33417177.
• Kartal Baykan E, Erdoğan M. Basal and pentagastrin-stimulated calcitonin cut-off values in diagnosis of preoperative medullary thyroid cancer. Turk J Med Sci. 2021 Apr 30;51(2):650-656. doi: 10.3906/sag-2003-182. PMID: 33128357; PMCID: PMC8203141.

Studies on COVID-19 and Other Applications (2020-2019)

• Balakrishnan V, Lakshminarayanan K. Screening of FDA Approved Drugs Against SARS-CoV-2 Main Protease: Coronavirus Disease. Int J Pept Res Ther. 2021;27(1):651-658. doi: 10.1007/s10989-020-10115-6. Epub 2020 Sep 28. PMID: 33013255; PMCID: PMC7521772.
• Achilonu I, Iwuchukwu EA, Achilonu OJ, Fernandes MA, Sayed Y. Targeting the SARS-CoV-2 main protease using FDA-approved Isavuconazonium, a P2-P3 α-ketoamide derivative and Pentagastrin: An in-silico drug discovery approach. J Mol Graph Model. 2020 Dec;101:107730. doi: 10.1016/j.jmgm.2020.107730. Epub 2020 Sep 2. PMID: 32920239; PMCID: PMC7462840.
• Durk MR, Jones NS, Liu J, Nagapudi K, Mao C, Plise EG, Wong S, Chen JZ, Chen Y, Chinn LW, Chiang PC. Understanding the Effect of Hydroxypropyl-β-Cyclodextrin on Fenebrutinib Absorption in an Itraconazole-Fenebrutinib Drug-Drug Interaction Study. Clin Pharmacol Ther. 2020 Dec;108(6):1224-1232. doi: 10.1002/cpt.1943. Epub 2020 Jul 18. PMID: 32535897; PMCID: PMC7689742.
• Gesenberg C, Mathias NR, Xu Y, Crison J, Savant I, Saari A, Good DJ, Hemenway JN, Narang AS, Schartman RR, Zheng N, Buzescu A, Patel J. Utilization of In Vitro, In Vivo and In Silico Tools to Evaluate the pH-Dependent Absorption of a BCS Class II Compound and Identify a pH-Effect Mitigating Strategy. Pharm Res. 2019 Oct 21;36(12):164. doi: 10.1007/s11095-019-2698-0. PMID: 31637544.
• Gambardella C, Offi C, Patrone R, Clarizia G, Mauriello C, Tartaglia E, Di Capua F, Di Martino S, Romano RM, Fiore L, Conzo A, Conzo G, Docimo G. Calcitonin negative Medullary Thyroid Carcinoma: a challenging diagnosis or a medical dilemma? BMC Endocr Disord. 2019 May 29;19(Suppl 1):45. doi: 10.1186/s12902-019-0367-2. PMID: 31142313; PMCID: PMC6541563.
• Šíma M, Kutinová-Canová N, Ryšánek P, Hořínková J, Moškořová D, Slanař O. Gastric pH in Rats: Key Determinant for Preclinical Evaluation of pH-dependent Oral Drug Absorption. Prague Med Rep. 2019;120(1):5-9. doi: 10.14712/23362936.2019.5. PMID: 31103048.
• Dillon C, Hughes H, O'Reilly NJ, Allender CJ, Barrow DA, McLoughlin P. Dissolving microneedle based transdermal delivery of therapeutic peptide analogues. Int J Pharm. 2019 Jun 30;565:9-19. doi: 10.1016/j.ijpharm.2019.04.075. Epub 2019 Apr 29. PMID: 31047995.
• Koziolek M, Grimm M, Bollmann T, Schäfer KJ, Blattner SM, Lotz R, Boeck G, Weitschies W. Characterization of the GI transit conditions in Beagle dogs with a telemetric motility capsule. Eur J Pharm Biopharm. 2019 Mar;136:221-230. doi: 10.1016/j.ejpb.2019.01.026. Epub 2019 Jan 28. PMID: 30703546.