BB₂R ligand research reagent

Phenacetin | COX inhibitor | CAS 62-44-2 | Selleck

research use only

Chemical Structure

Molecular Weight: 179.22

Citations

• Cell Stem Cell,2023,30(5):617-631.e8
• Drug Metab Dispos,2025,53(4):100049

17 Nobel Prize winners have used Selleck products

• Shimon Sakaguchi Nature Communications 2025,16, Article number:1325
• David Baker Dev Cell 2023, 58(20):2163-2180.e9.
• David Julius Cell 2017, 185-198.e16
• Michael Houghton Cell Chem Biol, 2020, 27(7):780-792.e5
• Charles M. Rice Cell 2018, 172(3):423-438.e25

Quality Control

Batch:S257701 DMSO]36 mg/mL]false]Ethanol]36 mg/mL]false]Water]Insoluble]false Purity: 100%

• Cited in Nature Medicine for its top-tier quality
• COA
• NMR
• HPLC
• SDS
• Datasheet

Solubility

In vitro batch selection

In vitro

Batch:DMSO : 36 mg/mL (200.87 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) Ethanol : 36 mg/mL Water : Insoluble

Molarity Calculator

Dilution Calculator Molecular Weight Calculator

In vivo batch selection

In vivo

Batch: Oral Administration Homogeneous suspension CMC-NA≥5mg/ml Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal: μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

DMSO percentage % DMSO Second solvent percentage % Tween 80 percentage % Tween 80 Water (ddH₂O) percentage % ddH 2 O DMSO percentage % DMSO + Corn oil percentage %

Calculation results: Working concentration: mg/ml; Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. ) Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH 2 O, mix and clarify. Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify. Note: 1. Please make sure the liquid is clear before adding the next solvent. 2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Mechanism of Action

Specificity

Expand to Check More

1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Signaling Pathway Map