Helen Frankenthaler Foundation

Fish osmoregulation research peptide

Mastoparan X | CAS 72093-22-2

Mastoparan X

Cat. No. 1896

Discontinued Product

1896 has been discontinued.

Description

G protein activator peptide

Biological Activity

Amphiphilic G protein activator peptide that binds to G i and G o. Also binds with high affinity to calmodulin (K d ~ 0.9 nM) and inhibits sarcoplasmic reticulum Ca 2+-ATPase (K i = 4.4 mM).

Technical Data

PropertyValue
M. Wt1555.98
FormulaC 73 H 126 N 20 O 15 S
SequenceINWKGIAAMAKKLL (Modifications: Leu-14 = C-terminal amide)
StorageDesiccate at -20°C
CAS Number72093-22-2
Smiles[H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

  • Certificate of Analysis / Product Datasheet
  • Safety Datasheet

References

References are publications that support the biological activity of the product.

  • Higashijima et al (1990) Regulation of G i and G o by mastoparan, related amphiphilic peptides, and hydrophobic amines. J.Biol.Chem. 265 14176
  • Longland et al (1999) The mechanism of inhibition of the Ca 2+-ATPase by mastoparan. J.Biol.Chem. 274 14799
  • Sukumar and Higashijima (1992) G protein-bound conformation of mastoparan-X, a receptor-mimetic peptide. J.Biol.Chem. 267 21421
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Keywords

Mastoparan X, Mastoparan X supplier, G, protein, activators, peptide, Gi, Go, Heterotrimeric, MastoparanX, G-protein, GTPases, 1896, Tocris Bioscience

Citations for Mastoparan X

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