GLP-2 (1-33) human CAS 223460-79-5

Human Glucagon-Like Peptide-1 Receptor Reporter Assay System

A nuclear receptor cell-based reporter assay

Features

• Screen test samples to quantify functional activity, either agonist or antagonist, that they may exert against human GLP-1R
• Robust technology provides sustained response for consistent and reproducible data acquisition
• Included in kit: Ready-to-use, pre-transfected reporter cells | Optimized media | Reference agonist | Luciferase detection reagent | Cell culture ready assay plate

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Product Categories

Product Type

Assay & Reagent Kits

Assay Kits

Cell-Based Assays

Research Area

Endocrinology & Metabolism

Hormones & Receptors

Metabolic Diseases

Diabetes

Application

Cell-Based Assay

Item No. 41520

Technical Information

Shipping & Storage Information

Storage

-80°C

Shipping

Dry ice in continental US; may vary elsewhere

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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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96 Well$1,092Confirm availability

384 Well$2,749Confirm availability

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This product has been produced by Indigo Biosciences

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Product Description

This assay utilizes proprietary human cells that provide constitutive expression of the Human Glucagon-like Peptide-1 Receptor (GLP-1R). The GLP-1R belongs to a class B G protein-coupled Receptor (GPCR), which is activated by several forms of GLP-1. GLP-1 is the second incretin hormone identified in the intestinal epithelial endocrine L-cells, followed by gastric inhibitory polypeptide (GIP). GLP-1/GLP-1R mainly regulates insulin secretion in response to high blood glucose levels. This receptor system plays a crucial role in energy homeostasis. Upon the ligand binding of GLP-1, GLP-1R signals through Gαs to drive an increase i