IGF-I Analog

Plain Text Title: Insulin-like Growth Factor 1 (IGF-1)

Insulin-like Growth Factor 1 (IGF-1)

Test Code: 010363

Test Overview

Insulin-like Growth Factor 1 (IGF-1) is a hormone that plays a critical role in childhood growth and continues to have anabolic effects in adults. This test measures the level of IGF-1 in the blood.

Clinical Applications

The IGF-1 test is primarily used to help identify growth hormone (GH) deficiency or excess. It is often ordered in conjunction with other tests to evaluate pituitary function.

Common Uses

Evaluate growth hormone deficiency in children and adults.
Assist in the diagnosis of acromegaly and gigantism.
Monitor the effectiveness of treatment for growth hormone disorders.

Specimen Requirements

A blood sample is required for this test.

Collection and Handling

Specimen Type: Serum
Collection: Standard venipuncture
Handling: Allow the blood to clot and centrifuge to separate serum.

Interpretation of Results

Results are interpreted in the context of the patient's age and sex, as normal ranges vary significantly. Abnormal levels may indicate various conditions.

Potential Findings

Result	Possible Indication
Low IGF-1	Growth hormone deficiency, malnutrition, liver disease.
High IGF-1	Acromegaly, gigantism, pituitary tumor.

Additional Information

IGF-1 levels are more stable throughout the day compared to growth hormone levels, which fluctuate, making it a useful screening test. For comprehensive evaluation, further dynamic testing of GH secretion may be required.

Note

This information is intended for healthcare professionals. Always consult clinical guidelines and consider the full clinical picture when interpreting test results.