Helen Frankenthaler Foundation

Multiple sclerosis research reagent​

Tools to support your multiple sclerosis research | Abcam

Tools to support your multiple sclerosis research

Multiple sclerosis (MS) is a complex inflammatory disorder caused by interactions between genetic and environmental factors. This complexity results in heterogeneity in clinical expression and treatment response, driving development of personalized therapeutics to improve patient outcomes.

To better understand the underlying causes of MS and uncover novel biomarkers and therapeutic targets, you need reliable reagents to targets related to immunomodulation, demyelination and related pathways.

Move ahead in your multiple sclerosis studies with the ultimate catalog of gold-standard recombinant antibodies and immunoassays. Our industry-leading validation processes give you reagents that work first time, every time and over time so you can have confidence in your results.

Browse our curated portfolio to discover how our reagents can help you study immunomodulation, demyelination and more.

Over years of research, we have started to learn more about the important role of the immune system in the pathogenesis of MS, which involves the recurrent invasion of the brain and spinal cord by both T and B cells. Accelerate your studies of the role of the immune system in MS with our premium recombinant antibodies. Our broad range of highly reproducible, recombinant antibodies includes conjugates and carrier-free formulations for flow cytometry, so you can find the right tools to support your research.

Browse our curated range of gold-standard antibodies to key immune targets in MS, including a variety of solutions for CD20 study.

Product highlights

abcam:product-category/primary-antibodies

ab64088

Anti-CD20 antibody [SP32]

  • Broadly validated in all traditional applications with human, mouse and rat samples
  • Knock-out validated
  • Advanced validation

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abcam:product-category/primary-antibodies

ab78237

Anti-CD20 antibody [EP459Y]

  • Broadly validated in all traditional applications with human samples
  • Knock-out validated

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abcam:product-category/primary-antibodies

ab279298

Anti-CD20 antibody [EP459Y] - Mouse IgG1 (Chimeric)

  • Engineered using recombinant technology
  • Provides ultimate reliability when multiplexing with other host species

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TargetabIDProduct nameHost speciesListed applications
BTKab208937Anti-BTK antibody [EPR20445]RabbitIP, WB, ICC/IF, Flow Cyt (Intra), IHC-P
BTKab68217Anti-BTK (phospho Y223) antibody [EP420Y]RabbitIP, Dot, WB
CD20ab64088Anti-CD20 antibody [SP32]RabbitFlow Cyt (Intra), ICC/IF, IHC-P, IP, WB, mIHC
CD20ab310536Alexa Fluor® 594 Anti-CD20 antibody [SP32]RabbitAntibody Labelling, Target Binding Affinity
CD20ab307132Alexa Fluor® 488 Anti-CD20 antibody [SP32]RabbitIHC-P
CD20ab312067Alexa Fluor® 555 Anti-CD20 antibody [SP32]RabbitAntibody Labelling, Target Binding Affinity
CD20ab78237Anti-CD20 antibody [EP459Y]RabbitFlow Cyt (Intra), ICC/IF, IHC-P, IP, WB
CD20ab198943Alexa Fluor® 647 Anti-CD20 antibody [EP459Y]RabbitFlow Cyt (Intra), mIHC
CD20ab198941Alexa Fluor® 488 Anti-CD20 antibody [EP459Y]RabbitFlow Cyt (Intra)
CD20ab279298Anti-CD20 antibody [EP459Y] - Mouse IgG1 (Chimeric)MouseMouse Flow Cyt (Intra), ICC, IP, WB
CD40ab213205Anti-CD40 antibody [EPR20540]RabbitIHC-P, WB
CD40ab224639Anti-CD40 antibody [EPR20735]RabbitFlow Cyt, ICC/IF, IHC-P, IP, WB
CD40ab302830Alexa Fluor® 647 Anti-CD40 antibody [EPR20735]RabbitFlow Cyt, ICC/IF
CD40ab302800Alexa Fluor® 594 Anti-CD40 antibody [EPR20735]RabbitFlow Cyt, ICC/IF
CD52ab234412Anti-CD52 antibody [CD52/2276RRabbitIHC-P
CD52ab245681Anti-CD52 antibody [Campath-1H]RabbitFlow Cyt, IHC-P
CD58ab196648Anti-CD58 antibody [EP15041]RabbitWB
IL-2 Receptor alphaab231441Anti-IL-2 Receptor alpha antibody [SP176]RabbitICC/IF, IHC-P, WB
Interferon- Betaab85803Anti-Interferon beta antibodyRabbitWB, ICC/IF
Complement your investigation of immunomodulation in brain and CNS tissues with our neuronal marker guide.

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Repairing the myelin sheath is a key focus for multiple sclerosis research. Assessing disease progression and the effectiveness of repair mechanisms requires reliable antibodies that can be used in immunohistochemical analysis of brain and CNS tissue.

Assess myelin sheath integrity with our precision recombinant antibodies, broadly validated across applications including IHC. Our in-house recombinant antibodies are tested in tissue microarrays (TMA), including brain tissue samples, to ensure optimal performance in your experiments.

Product highlights

abcam:product-category/primary-antibodies

ab7349

Anti-Myelin Basic Protein antibody [12]

  • Cited in over 300 publications
  • Validated in western blot, IHC-P and ICC/IF with human samples

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abcam:product-category/primary-antibodies

ab183868

Anti-Myelin Protein Zero antibody [EPR20383]

  • Suitable IHC-Fr, IHC-P, western blot and IP
  • Reacts with human, mouse and rat samples

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abcam:product-category/primary-antibodies

ab277254

Anti-MAG/GMA antibody [EPR24276-125]

  • Suitable for ICC/IF, western blot and IHC-Fr/IP
  • Reacts with human, mouse and rat samples

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TargetabIDProduct nameHost speciesListed applications
CNPaseab6319Anti-CNPase antibody [11-5B]MouseICC/IF, WB, IHC-P
CNPaseab227218Anti-CNPase antibodyRabbitWB, IHC-P, IHC-Fr
MAG/GMAab277524Anti-MAG/GMA antibody [EPR24276-125]RabbitICC/IF, IHC-Fr, IHC-P, IP, WB
MAG/GMAab46803Anti-MAG/GMA antibody [EP971Y]RabbitWB
Myelin Basic Proteinab7349Anti-Myelin Basic Protein antibody [12]RatICC/IF, IHC-P, WB
Myelin Basic Proteinab218011Anti-Myelin Basic Protein antibody [EPR21188]RabbitIHC-Fr, IHC-P, WB
Myelin Basic Proteinab321395Alexa Fluor® 750 Anti-Myelin Basic Protein antibody [EPR21188]RabbitAntibody Labelling,