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Sovateltide is a 14-amino acid polypeptide with a large number of carboxyl groups in the sequence and strong biological activity.
Sovateltide is a highly selective endothelin B receptor agonist that increases blood flow, shows anti-apoptotic activity, protects neural mitochondria, and promotes neural vascular remodeling. In May 2023, the drug was approved in Japan for the treatment of hypertensive acute cerebral ischemic stroke.
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