Helen Frankenthaler Foundation

Frog neuropeptide

Neurokinin A (porcine) | CAS 86933-74-6 | NKA

peptides molecular research

Neurokinin A (porcine)

Cat. No. 1152. Discontinued Product. 1152 has been discontinued.

Description

Endogenous tachykinin peptide. Alternative Names: NKA.

Biological Activity

Endogenous tachykinin peptide; more potent bronchoconstrictor than Substance P.

Technical Data

PropertyValue
M. Wt1133.3
FormulaC50 H80 N14 O14 S
SequenceHKTDSFVGLM (Modifications: Met-10 = C-terminal amide)
StorageDesiccate at -20°C
CAS Number86933-74-6
PubChem ID5311311
InChI KeyHEAUFJZALFKPBA-JPQUDPSNSA-N
Smiles[H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. Tocris products are intended for laboratory research use only, unless stated otherwise.

References

References are publications that support the biological activity of the product.

  • Lippe et al (1997) Neurokinin A-induced vasoconstriction and muscular contraction in the rat isolated stomach: mediation by distinct and unusual neurokinin A 2 receptors. J.Pharmacol.Exp.Ther. 281 1294 PMID:9190865
  • Nawa et al (1983) Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursor. Nature 306 32 PMID:6195531
  • Sherwood et al (1997) Bronchoconstrictor and respiratory effects of neurokinin A in dogs. J.Pharmacol.Exp.Ther. 283 788 PMID:9353399
Citations

Citations are publications that use Tocris products. Selected citations for Neurokinin A (porcine) include:

  • Gutierrez and Boada (2019) Neuropeptide-induced modulation of carcinogenesis in a metastatic breast cancer cell line (MDA-MB-231LUC+). Cancer Cell Int 18 216 PMID:30598641
Reviews

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